Absolutely.
That's the thing I hate about tissue warnings - you're assuming that you're going to do it right. With this show? I'm not so sure that's going to happen, haha. It's like when fic writers write stuff like, "You're not gonna be able to handle what's in this chapter. Get your tissues ready!"
I assure you, I will be able to handle it. And I'd be more likely to cry about it if I didn't know it was coming.