Reportedly, after Marisa Tomei turned down the part of Carrie in Four Weddings and a Funeral, Jeanne Tripplehorn was cast but pulled out just before filming began due to her mothers death. Not sure Tripplehorn would have been much of an improvement over Andie MacDowell (who many, including me, see as the weak link in the cast), but I think Tomei could have done a lot more with the role.