Sentient Worlds Observation and Response Department. It does the same job as SHIELD, but for external (alien) threats, not internal (human) ones.
The one think that's throwing me a little is that they're mixing up the time periods of the sitcoms. The first episode was a plot that was pure Bewitched, but they had Wanda styled to look like a 50s sitcom housewife (e.g. Ozzie and Harriet). Then we get the Bewitched theme and styling on the house, but Wanda was made up to look like Mary Tyler Moore on Dick Van Dyke. The pants thing is even a reference, because the network censors were very resistant to the idea of Laura wearing something that let you see her butt.
I don't mind mixing the references, it just seems odd that they're not more discretely doing 50s then 60s etc.