I'm up for anything, but personally I'd be really jazzed to do a straight character elimination round, because like @deaja I was not around when/if that was done in the past. I think it would be ok to do more substantial characters with ones that are slightly less so, just because I'd really enjoy seeing who came out on top in terms of Lorelai/Rory, Emily/Richard, the boyfriends and best friends, etc..in fact that's what I'd be most excited about, and there could be surprises as far as secondary characters being more popular then main ones....so maybe if we don't do main characters this round, we can do them another time? Same line of thought, maybe we could do episodes at some point? I understand if that's too 'done' though!
That said, townies would be fine too..I think of any group, that would be the one with the most variety..but then do we exclude more main characters like Luke, Lane, and Sookie? I'd also be cool with Emily/Richard..really I just like playing this game!