I was suprised to see that PTV doesn't yet have a webcomics main thread, so here it is!
What's everybody reading, and does anyone have any recommendations?
Of course, there's xkcd, Cyanide and Happiness, The Oatmeal, Dinosaur Comics, Saturday Morning Breakfast Cereal, etc. that are all pretty great.
Here are just a few to start us off with!
Hark, a Vagrant! http://www.harkavagrant.com/ - Kate Beaton's wonderful series of humerous comics about various aspects of history. Not updated that frequently, but usually clever and amusing.
Anything by Emily Carroll http://www.emcarroll.com/ - So, SO creepy. The master of the horror comic short story. I'd really recommend "His Face All Red" as your first venture into the world of Emily Carroll, but "Margot's Room" and "Out of Skin" are really, really fantastic. Her first book, Through the Woods, just came out today, and it's AMAZING.
Perry Bible Fellowship http://pbfcomics.com/ - Recently started updating again! Ugh, one of my absolute favorite gag comics. Super clever and surreal, with an iconic art style.
Three Word Phrase http://threewordphrase.com/ Often as hilarious as PBF, but less-known.