Maybe I've been watching too much Miss Marple..but what if....NOBODY killed Wes...Maybe he commited suicide...and was on the bed when Nate entered Annalise's bedroom thus exxplaining the stunned look on Nate's face ???? Remember nobody in the hospital mentioned HOW he died...only that he had died BEFORE the fire..As for the fire...You all saw Annalise put a bottle of vodka. on top of the mantel...over a raging fire...and left the house...And as the explosion which was shown outside the house seems to have been on the ground floor...at the front of the house where her study was...it could be that the bottle fell into the fire and exploded...and spread to more combustable materials...Just a thought.