While the cliffhanger was a little over the top, I actually think the ending may have signified Owen and/or Teddy leaving.
Winston mentioning he's not the only cardio surgeon meaning the only way to build romantic tension with him and Jules is for him to be the only one. Teddy being so antsy being around Owen, like she was itching to get away from him and the hospital. Owen telling Teddy she made history with the surgery, which would give her grounds to work anywhere else (Hell, maybe she'll go hang with Burke and Christina). This didn't seem like just the end of their marriage but maybe the end of their characters. Maybe Teddy or Owen were in the room near the explosion. I don't know what the writers would do with Owen if Teddy left, so I feel like they both have to go together. His character seems kind out of gas. His story lines are only about his feelings being hurt, him self-righteously chasing some goal, or his bad relationships and it's been that way for years.
Also, if Teddy dies, Ben gets to stay at the hospital and I doubt they're writing out Ben and Bailey. My guess is Ben's behavior would cause more story tension if Bailey were the chief and had to deal with it.
Not to mention, the show is pretty expensive now and getting rid of a few leads would decrease costs, so I'm sure they're going to kill someone. My money is on Linc, Teddy, and/or Owen.
Also, they really have to cut it with the Richard's takes something Meredith or Bailey does personally. We get it. Meredith and Bailey are surrogate daughters for him and they see him as a father figure. But even if they were his kids, they would still have jobs, lives and dreams of their own and this is like the eigth time they've done this story (the second time this season with him arguing with Meredith about Catherine).