At the end of the first episode I thought "well, I think I liked that". I'm still not completely sure, but I will watch the next episode.
There were some things that stood out - I'm partial to Sheen and absolutely loved his scene-chewing. Lou Diamond Philips cemented his place with his role on Psych, so even though I wasn't super impressed with his scenes he gets a pass. I liked Payne, but I do hope he settles in a little better as the show goes on. A pilot is often uneven, so I'm willing to see what happens in a couple more episodes.
And while I liked the mother well enough, I found it distracting that she appears so young - too young to be Malcolm's mother. And then there's the sister. I cannot take her seriously as some intrepid reporter, so that was also a distraction. I like the female cop, and am open on the male cop. It'll take a little more than we saw of him to decide if he's going to just be the stock character opposed to the civilian consultant.
I do think there will be more layers exposed for Malcolm. I don't know if it was script or just actor, but the exultant look on his face when he came out of the building after chopping of the guys hand was creepy.
