I would watch it, with a few caveats. I'm a big fan of Jimmi Simpson, so I'd definitely be down to see him continuing in the role. Joey is more "meh" for me, though I suspect him being Amy Acker's real life husband was more about why they brought him in for the one shot episode here. Harper is fine, could take or leave her. Wouldn't mind seeing Gen come back (say, if the series were set a few years in the future).
Having said that, if they brought it back like it was in S1 and a chunk of S2, where it was just a POI of the week format, I'd probably pass. I almost gave up on the show, before they switched to the serialized plot.
Edited to add: I would watch the crap out of a spinoff show featuring Zoe being a fixer.