This entire saga with Sean and how much time, effort and resources the show put into filming his years of deterioration leading to his death is an object lesson in exactly what you stated.
There are people who can benefit from addiction treatment and there are those who cannot. I worked for YEARS with criminal defendants (over 90% of whom suffered from co-occurring disorders--substance abuse AND mental illness). The drugs they used were illegal so they wound up charged with crimes. I studied and applied so much research in the field (my graduate work included) and had innumerable resources that the courts permitted me to use to try and reduce recidivism.
In the end, I would say the stat of 5% success that Dr. Now uses for the food addicts (and mental health sufferers) also applied to the probably thousands of clients I worked with over many years.
There were those who were simply too damaged by circumstances, like their first five years of life (that they HAD NOTHING TO DO WITH CREATING) to muster up the energy needed to learn discipline, guidelines, routines and healthy ways of coping with life that would have allowed them to make the positive changes they would have needed to live functional, productive lives.
There ARE those who can overcome a treacherous childhood, absolutely!! However, for the majority this early emotional, physical, spiritual and intellectual deprivation is too much to overcome and they spend a lifetime of self-destruction.
At least Sean was spared the ultimate deprivation of being incarcerated in a jail facility. I am thankful for that small favor.