Here's some questions to next season and maybe the next book will be released before it but I'm not counting on it.
The most important question is how Bran will adapt to his roll as the Three Eye Raven and what role will he play (past or future) in the great war to come?
What will Jaime do with "Queen" Cersei? The show prophecy for Cersei is complete.
How in the world will they stop Dany from taking the Iron Throne? What army is left to defend what's left of King's Landing?
What's Littlefinger and Sansa's next move? Is Sansa pregnant?
How will Euron Greyjoy play into next season?
Will Jon ever know of his true lineage?
Will I ever hear Tyrion's brothel story?